HIV血清反应阳性患者的头颈部病毒感染

Viral infections of the head and neck among HIV-seropositive patients.

作者信息

Eversole L R

机构信息

Section of Oral Diagnosis, Oral Medicine and Oral Pathology, School of Dentistry, UCLA Health Sciences Center 90024.

出版信息

Oral Surg Oral Med Oral Pathol. 1992 Feb;73(2):155-63. doi: 10.1016/0030-4220(92)90188-v.

DOI:10.1016/0030-4220(92)90188-v

PMID:1312690

Abstract

Many viruses cause opportunistic infections in HIV-positive patients. Those that cause oral lesions include herpes simplex, varicella zoster, Epstein-Barr virus, cytomegalovirus, and papillomavirus. Importantly, many of the herpes-group viruses are able to augment immunosuppression and some actually transactivate HIV replication-inducing genetic sequences. This article reviews the role of viral agents in the activation of HIV replication and details the features of the reported oral lesions that represent viral opportunistic infections.

摘要

许多病毒会在艾滋病毒呈阳性的患者中引发机会性感染。那些可导致口腔病变的病毒包括单纯疱疹病毒、水痘带状疱疹病毒、爱泼斯坦-巴尔病毒、巨细胞病毒和乳头瘤病毒。重要的是，许多疱疹病毒能够增强免疫抑制作用，有些实际上还能反式激活诱导HIV复制的基因序列。本文综述了病毒因子在HIV复制激活中的作用，并详细阐述了所报道的代表病毒性机会性感染的口腔病变特征。