Leatham E W, Eeles R, Sheppard M, Moskovic E, Williams M P, Horwich A, Mitchell D N
Royal Marsden Hospital, London, UK.
Clin Oncol (R Coll Radiol). 1992 Mar;4(2):89-95. doi: 10.1016/s0936-6555(05)80973-2.
Sarcoid-type pulmonary lymphadenopathy associated with testicular cancer is a rare condition which has been previously reported in only 14 cases. Earlier case reports have failed to distinguish between generalized sarcoidosis as opposed to a local granulomatous reaction to tumour. We describe a further 8 cases of the association and provide strong supportive evidence for systemic sarcoidosis in 5 of our patients. In 3 of our patients with systemic sarcoidosis there was coexisting testicular cancer requiring additional treatment. We therefore advise caution in the interpretation of the clinical and histological findings in these patients, and recommend thorough investigation of all such cases.
与睾丸癌相关的结节病样肺淋巴结病是一种罕见病症，此前仅报道过14例。早期病例报告未能区分全身性结节病与肿瘤局部肉芽肿反应。我们描述了另外8例这种关联病例，并为5例患者的全身性结节病提供了有力支持证据。在3例全身性结节病患者中，同时存在需要额外治疗的睾丸癌。因此，我们建议在解读这些患者的临床和组织学发现时要谨慎，并建议对所有此类病例进行全面检查。
