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巨细胞病毒作为孤立性严重回肠出血的病因

Cytomegalovirus as a cause of isolated severe ileal bleeding.

作者信息

Weber F H, Frierson H F, Myers B M

机构信息

Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville.

出版信息

J Clin Gastroenterol. 1992 Jan;14(1):52-5. doi: 10.1097/00004836-199201000-00013.

DOI:10.1097/00004836-199201000-00013
PMID:1313469
Abstract

A 66-year-old man with squamous cell carcinoma of the tongue and vallecula had massive lower gastrointestinal hemorrhage. Colonoscopy examination results were normal, but angiography revealed a 3 x 6-cm hypervascular mass in the right lower quadrant. Persistent bleeding required resection of a large ileal ulcer, which proved to be an isolated ulcer containing cells with cytomegalovirus (CMV) inclusion bodies. Massive gastrointestinal hemorrhage due to an isolated CMV ileal ulcer in adults without acquired immunodeficiency syndrome has not been previously reported. This case illustrates that hemorrhage due to CMV infection of the ileum may occur in the absence of endoscopic evidence of colonic involvement.

摘要

一名66岁患有舌和会厌谷鳞状细胞癌的男性出现大量下消化道出血。结肠镜检查结果正常,但血管造影显示右下腹有一个3×6厘米的高血管性肿块。持续出血需要切除一个大的回肠溃疡,结果发现这是一个孤立的溃疡,含有带有巨细胞病毒(CMV)包涵体的细胞。成人无获得性免疫缺陷综合征时,孤立性CMV回肠溃疡导致大量胃肠道出血此前尚未见报道。该病例表明,在没有结肠受累的内镜证据的情况下,回肠CMV感染也可能导致出血。

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