Satterwhite L L, Pollard T D
Department of Cell Biology and Anatomy, Johns Hopkins Medical School, Baltimore, Maryland 21205.
Curr Opin Cell Biol. 1992 Feb;4(1):43-52. doi: 10.1016/0955-0674(92)90057-j.
The actomyosin contractile-ring mechanism remains the paradigm for cytokinesis after 20 years of experimental testing. Recent evidence suggests that Ca2+ triggers the contraction and that cell-cycle kinases regulate the timing of cytokinesis. New work is required to identify the signals from the mitotic spindle that specify the position of the furrow.
经过20年的实验验证，肌动球蛋白收缩环机制仍是胞质分裂的范例。最近的证据表明，Ca2+触发收缩，细胞周期激酶调节胞质分裂的时间。需要开展新的研究来确定来自有丝分裂纺锤体的指定沟位置的信号。
