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骨髓移植相关的病毒感染

Virus infections complicating bone marrow transplantation.

作者信息

Rogers T R

机构信息

Department of Medical Microbiology, Charing Cross and Westminster Medical School, London.

出版信息

Clin Ter. 1992 Feb;140(2):131-6.

PMID:1314724
Abstract

Virus infections account for considerable morbidity in bone marrow transplant (BMT) recipients. In all ages, members of the herpes virus group are the predominant pathogens. Of these, cytomegalovirus is pre-eminent in being the most frequent cause of death due to infection associated with the transplant procedure. Considerable effort is being invested in the development of preventative and therapeutic strategies to control this virus. Other potentially life-threatening virus infections may be acquired on the transplant unit as a result of cross-infection and can be caused by enteroviruses, rotaviruses and adenoviruses. Prevention of these infections is best achieved by implementation of strict infection-control measures.

摘要

病毒感染在骨髓移植(BMT)受者中导致相当高的发病率。在所有年龄段中,疱疹病毒组的成员是主要病原体。其中,巨细胞病毒在因移植相关感染导致的死亡原因中最为突出,是最常见的病因。目前正在投入大量精力研发控制这种病毒的预防和治疗策略。其他潜在威胁生命的病毒感染可能因交叉感染在移植病房获得,可由肠道病毒、轮状病毒和腺病毒引起。通过实施严格的感染控制措施,可最佳地预防这些感染。

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