Malcus P, Laurini R, Marsál K
Department of Obstetrics and Gynecology, University of Lund, Malmö General Hospital, Sweden.
Acta Obstet Gynecol Scand. 1992 Jan;71(1):39-45. doi: 10.3109/00016349209007945.
Combined real-time ultrasound and pulsed Doppler ultrasound examinations were performed in 67 patients with third trimester hemorrhage and other symptoms related to placental abruption, starting from the onset of symptoms to delivery. In 52 of the cases, placental morphology was investigated by light microscopy. Thirteen patients were ultimately given the diagnosis abruptio placentae. None of the morphological placental changes considered had any statistical relationship to placental abruption. Patients with placental centrocotyledon hemorrhages and infarction more often had abnormal umbilical artery flow velocity waveforms at the onset of symptoms, and more frequent abnormal arcuate artery flow velocity waveforms were found among those with placental infarction alone. Abnormal flow velocity waveforms in the umbilical and arcuate arteries were associated with placental abruption, both at the onset of symptoms and at the final examination before delivery. The results indicate an increased risk for placental abruption if the arcuate and/or umbilical artery flow velocity waveforms are abnormal in patients with third trimester hemorrhage.
对67例孕晚期出血及其他与胎盘早剥相关症状的患者进行了实时超声和脉冲多普勒超声联合检查，检查从症状出现开始直至分娩。其中52例通过光学显微镜研究胎盘形态。最终13例患者被诊断为胎盘早剥。所考虑的胎盘形态学改变与胎盘早剥均无统计学关联。有胎盘中央小叶出血和梗死的患者在症状出现时脐动脉血流速度波形异常更为常见，而仅胎盘梗死患者中弓形动脉血流速度波形异常更为频繁。脐动脉和弓形动脉的血流速度波形异常在症状出现时以及分娩前的最终检查时均与胎盘早剥相关。结果表明，孕晚期出血患者若弓形动脉和/或脐动脉血流速度波形异常，则发生胎盘早剥的风险增加。
