Zhang D, Hendricks D G, Mahoney A W
Department of Nutrition and Food Sciences, Utah State University, Logan 84322-8700.
Plant Foods Hum Nutr. 1992 Apr;42(2):97-108. doi: 10.1007/BF02196462.
Effects of coprophagy and coprophagy preventing device on iron bioavailability were evaluated in two experiments. In Experiment 1, rats were fed diets with FeSO4, spinach, bran cereal or cornmeal as the iron source. The rats in each diet group were fitted with collars, sham-collars or not fitted with collars (control). In Experiment 2, rats were fed diets with FeSO4 or green peas as the iron source and were fitted with collars, tail cups, sham-collars or not fitted with any device (control). Preventing coprophagy reduced hemoglobin regeneration efficiency (HRE) of rats fed bran cereal, green peas, spinach or cornmeal diets by 26 (P less than .05), 24(P less than .05), 22(P less than .05) and 11% (not significant), respectively. Preventing coprophagy in rats fed FeSO4 diet did not significantly reduce HRE. Sham-collaring reduced (P less than .05) HRE of rats fed the FeSO4 diet by 12 and 13% but did not significantly affect HRE in rats fed food iron sources. It was more convenient and effective to prevent coprophagy with collars than with tail cups. Differences in bioavailability between food and FeSO4 iron due to coprophagy may be explained based on two gastrointestinal nonheme iron pools, complexed and highly soluble.
在两项实验中评估了食粪行为及食粪预防装置对铁生物利用率的影响。在实验1中，给大鼠喂食以硫酸亚铁、菠菜、麸皮谷物或玉米粉作为铁源的日粮。每个日粮组的大鼠分别佩戴项圈、假项圈或不佩戴项圈（对照）。在实验2中，给大鼠喂食以硫酸亚铁或青豆作为铁源的日粮，并给它们佩戴项圈、尾杯、假项圈或不佩戴任何装置（对照）。防止食粪行为分别使喂食麸皮谷物、青豆、菠菜或玉米粉日粮的大鼠的血红蛋白再生效率（HRE）降低了26%（P<0.05）、24%（P<0.05）、22%（P<0.05）和11%（不显著）。防止喂食硫酸亚铁日粮的大鼠食粪行为并未显著降低HRE。佩戴假项圈使喂食硫酸亚铁日粮的大鼠的HRE降低了12%和13%（P<0.05），但对喂食食物铁源的大鼠的HRE没有显著影响。用项圈防止食粪行为比用尾杯更方便有效。由于食粪行为导致的食物铁和硫酸亚铁铁生物利用率的差异，可能基于两个胃肠道非血红素铁池（络合态和高可溶性）来解释。
