Danilowicz D A
Br Heart J. 1976 May;38(5):516-22. doi: 10.1136/hrt.38.5.516.
Nine children with endocardial fibroelastosis were followed from the time of admission with congestive heart failure until either death or discharge. Review of multiple clinical features showed that only the electrocardiographic pattern could be correlated with death or survival. The presence of a delayed transition zone with anterior force loss on the initial electrocardiogram ('infarct pattern') was noted in all the children who died. Progression of these changes with a pattern of anterolateral 'infarct' in two and inferior wall 'infarct' in two occurred before death. Necropsy on three of the four children confirmed the diagnosis of endocardial fibroelastosis. There was extensive fibrosis and thinning of the left ventricular myocardium as well as involvement of the mitral valve structures. Review of published cases supports the view that an 'infarct' pattern in a child with endocardial fibroelastosis is usually associated with death and that this pattern is a negative prognostic sign for survival.
9例心内膜弹力纤维增生症患儿自因充血性心力衰竭入院起至死亡或出院一直接受随访。对多项临床特征进行回顾后发现，只有心电图表现与死亡或存活相关。所有死亡患儿的初始心电图均显示有延迟过渡区伴前向力丧失（“梗死图形”）。其中2例出现前侧壁“梗死”图形、2例出现下壁“梗死”图形，这些改变在死亡前呈进行性发展。4例患儿中有3例尸检确诊为心内膜弹力纤维增生症。左心室心肌有广泛纤维化及变薄，二尖瓣结构也受累。对已发表病例的回顾支持这样一种观点，即心内膜弹力纤维增生症患儿出现“梗死”图形通常与死亡相关，且该图形是存活的不良预后指标。
