[双侧大结节性肾上腺增生伴空蝶鞍及垂体前叶功能减退所致的促肾上腺皮质激素非依赖性库欣综合征]

[ACTH-independent Cushing's syndrome due to bilateral macronodular adrenal hyperplasia with empty sella turcica and anterior panhypopituitarism].

作者信息

Menéndez Torre E L, López Carballo M T, Rodríguez Erdozain R, Urbieta Echezarreta M, Lafita Tejedor J, Forga Llenas L

机构信息

Servicio de Endocrinología, Hospital de Navarra, Pamplona.

出版信息

Rev Clin Esp. 1992 Mar;190(5):261-3.

Abstract

A case is presented of Cushing's syndrome due to macronodular bilateral adrenal hyperplasia which is ACTH-independent as was demonstrated by the undetectable basal and after stimulation with metoprolol ACTH plasma levels. High cortisol levels is associated in this patient with empty sella turcica and anterior panhypopituitarism with confirm the exclusive adrenal origin of the hormone hypersecretion and the lack of treatment success with hypophysis ablation in this process.

摘要

本文报告一例由大结节性双侧肾上腺增生引起的库欣综合征，该增生不依赖促肾上腺皮质激素（ACTH），因为基础状态下及美托洛尔刺激后血浆ACTH水平均未检测到。该患者高皮质醇水平与空蝶鞍和垂体前叶功能减退相关，这证实了激素分泌过多仅源于肾上腺，且在此过程中垂体切除治疗未成功。

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1

[ACTH-independent Cushing's syndrome due to bilateral macronodular adrenal hyperplasia with empty sella turcica and anterior panhypopituitarism].[双侧大结节性肾上腺增生伴空蝶鞍及垂体前叶功能减退所致的促肾上腺皮质激素非依赖性库欣综合征]

Rev Clin Esp. 1992 Mar;190(5):261-3.

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Nodular adrenal hyperplasia with elevated adrenocorticotropic hormone levels.

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