Shih S C, Jeng K S, Yang K C, Hsu H W, Kao C R
Department of Medicine, Mackay Memorial Hospital, Taipei.
Zhonghua Yi Xue Za Zhi (Taipei). 1992 Mar;49(3):183-8.
In 332 patients of adenocarcinoma of the stomach and 7095 patients with duodenal ulcer collected in 5-year period, 21 cases were found to have both disease entities. With regard to clinical manifestations, gross morphology, microscopic differentiation and management of adenocarcinoma of the stomach, the patients with duodenal ulcer showed no significant difference from those without duodenal ulcer. The activities of the duodenal ulcers could be in acute active stage or present as chronic scar only. The ulcer history varied from several years to more than 15 years. We concluded that the frequency of adenocarcinoma of the stomach developed in patients with duodenal ulcer is not so rare, presentation of epigastric discomfort or signs of UGI bleeding in patients with duodenal ulcer history not always indicated recurrence of ulcer disease.
在5年期间收集的332例胃腺癌患者和7095例十二指肠溃疡患者中，发现21例同时患有这两种疾病。关于胃腺癌的临床表现、大体形态、显微镜下分化及治疗，十二指肠溃疡患者与无十二指肠溃疡患者无显著差异。十二指肠溃疡的活动期可为急性活动期或仅表现为慢性瘢痕。溃疡病史从数年到超过15年不等。我们得出结论，十二指肠溃疡患者发生胃腺癌的频率并不罕见，有十二指肠溃疡病史的患者出现上腹部不适或上消化道出血迹象并不总是提示溃疡病复发。
