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Identification and characterization of glycoprotein gp1 of bovine herpesvirus type 4.

作者信息

Dubuisson J, Pastoret P P, Thiry E

机构信息

Department of Virology-Immunology, Faculty of Veterinary Medicine, University of Liège, Belgium.

出版信息

J Gen Virol. 1992 May;73 ( Pt 5):1293-6. doi: 10.1099/0022-1317-73-5-1293.

DOI:10.1099/0022-1317-73-5-1293
PMID:1316948
Abstract

Three major bovine herpesvirus type 4 (BHV-4) glycoproteins have been described previously. By using monoclonal antibodies produced against BHV-4 envelope proteins from which the three major antigens had been removed by immunoaffinity, a fourth glycoprotein was identified. This protein (gp1) has a high Mr (greater than 300K), is detected about 8 h post-inoculation of infected cells and is strictly expressed as a gamma protein. Moreover, gp1 was identified by a polyclonal antiserum from an infected animal, indicating that this glycoprotein is an antigen recognized by the immune system of infected animals.

摘要

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