Yourassowsky E, Van der Linden M P, MacGilavry G B, Glupczynsky Y
Département de Microbiologie, Hôpital Universitaire Brugmann, Bruxelles.
Acta Clin Belg. 1992;47(1):15-20. doi: 10.1080/17843286.1992.11718205.
The difficulties encountered in measuring the susceptibility of the association amoxicillin/clavulanate can be a cause for disagreements between laboratories. With an inoculum standardized at 10(4) CFU/spot, the resistance level of E. coli approaches 10%. If the variety of current methods is taken into account, the evaluation of a resistance increase can only be an internal one, specific for each laboratory, provided that methods do not change in the course of time.
测量阿莫西林/克拉维酸联合制剂敏感性时遇到的困难可能导致实验室之间出现分歧。接种物标准化为每点10⁴CFU时,大肠杆菌的耐药水平接近10%。如果考虑到当前方法的多样性,只有在方法随时间不变的情况下,对耐药性增加的评估才只能是每个实验室特有的内部评估。