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粗糙脉孢菌per-1基因座上等位基因间的表型多样性。

Phenotypic diversity among alleles at the per-1 locus of Neurospora crassa.

作者信息

Howe H B

出版信息

Genetics. 1976 Apr;82(4):595-603. doi: 10.1093/genetics/82.4.595.

DOI:10.1093/genetics/82.4.595
PMID:131733
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1213482/
Abstract

Comparison of 11 perithecial color mutants suggested that all were alleles at the per-1 locus but nonetheless separable into two groups because of phenotypic differences. Three of the mutant strains produced orange perithecia and black ascospores, and eight produced paler, yellow perithecia and white ascospores. Perithecial phenotype was dependent upon the genotype of the protoperithecial parent; ascospore phenotype, upon the genotype of the individual ascospore. No evidence was found that the white ascospores were due to chromosomal rearrangements. No separation of the perithecial and ascospore phenotypes by recombination was observed in a cross between one of the mutants and a per-1+ strain. However, apparent low levels of recombination in crosses between some of the mutants indicated possible genetic complexity at the per-1 locus. The phase specificity of the per-1 mutations and the possible nature and mode of expression of the orange and yellow perithecial pigments are discussed.

摘要

对11个囊壳颜色突变体的比较表明,所有突变体都是per-1位点的等位基因,但由于表型差异仍可分为两组。其中三个突变菌株产生橙色囊壳和黑色子囊孢子,八个产生颜色较浅的黄色囊壳和白色子囊孢子。囊壳表型取决于原始子囊壳亲本的基因型;子囊孢子表型则取决于单个子囊孢子的基因型。未发现白色子囊孢子是由染色体重排导致的证据。在其中一个突变体与per-1+菌株的杂交中,未观察到通过重组分离囊壳和子囊孢子表型的情况。然而,一些突变体之间杂交中明显较低的重组水平表明per-1位点可能存在遗传复杂性。文中还讨论了per-1突变的阶段特异性以及橙色和黄色囊壳色素可能的性质和表达模式。

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本文引用的文献

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Genetic Determination of Tyrosinase Thermostability in Neurospora.脉孢菌中酪氨酸酶热稳定性的遗传决定因素
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A perithecial color mutant of Neurospora crassa.粗糙脉孢菌的子囊壳颜色突变体。
Mol Gen Genet. 1974;131(1):79-83. doi: 10.1007/BF00269389.