Droz J P, Lhommé C
Département de médecine, Institut Gustave-Roussy, Villejuif.
Rev Prat. 1992 Apr 1;42(7):817-22.
The term gestational trophoblastic tumours covers hydatidiform moles, invasive moles and choriocarcinomas. These are rare diseases remarkable for their high chemosensitivity. The current objective is to cure all patients while preserving their potential for child bearing. Several studies have elicited prognostic factors, so that treatment can be adjusted to each individual patient. Advances in immunochemistry have led to the discovery of a highly reliable marker (HCG and beta-HCG) which has proved valuable to confirm the diagnosis and to follow the patients during and after treatment.
妊娠滋养细胞肿瘤包括葡萄胎、侵蚀性葡萄胎和绒毛膜癌。这些是罕见疾病,以其高化疗敏感性而著称。当前的目标是治愈所有患者,同时保留其生育潜力。多项研究已得出预后因素,以便能够根据每位患者的具体情况调整治疗方案。免疫化学的进展已促成发现一种高度可靠的标志物(人绒毛膜促性腺激素和β-人绒毛膜促性腺激素),该标志物已证明在确诊以及治疗期间和治疗后对患者进行随访方面具有重要价值。