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A组葡萄球菌噬菌体的结构畸变

Structural aberrations in group A Staphylococcus bacteriophages.

作者信息

Ackermann H W, Berthiaume L, Sonea S, Kasatiya S S

出版信息

J Virol. 1976 May;18(2):619-26. doi: 10.1128/JVI.18.2.619-626.1976.

DOI:10.1128/JVI.18.2.619-626.1976
PMID:131865
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC515588/
Abstract

Six related Staphylococcus phages spontaneously produced various abnormal head and tail structures: (i) giant capsids which were tailed and apparently contained nucleic acid; (ii) regular and irregular smooth polyheads; (iii) heads and polyheads with wavy outlines; (iv) mottled heads and polyheads; (v) abnormally long and short tails; and (vi) "double capsids" connected by a small bridge. Some of these structures are rare, or have not yet been reported. The frequency os specific aberrant particles varied from one phage to another. Length distribution of smooth irregular polyheads and of abnormal tails indicated that these structures assemble at random from protein synthesized in excess. These phages represent an interesting model for genetic and morphogentic studies.

摘要

六种相关的葡萄球菌噬菌体自发产生了各种异常的头部和尾部结构

(i)有尾的巨大衣壳,显然含有核酸;(ii)规则和不规则的光滑多面体头部;(iii)轮廓呈波浪状的头部和多面体头部;(iv)斑驳的头部和多面体头部;(v)异常长和短的尾部;以及(vi)通过小桥连接的“双衣壳”。其中一些结构很罕见,或者尚未见报道。特定异常颗粒的频率因噬菌体而异。光滑不规则多面体头部和异常尾部的长度分布表明,这些结构是由过量合成的蛋白质随机组装而成的。这些噬菌体代表了遗传和形态发生研究的一个有趣模型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/0169282874e7/jvirol00221-0265-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/a06fc3e89199/jvirol00221-0263-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/d9b3ad1dc010/jvirol00221-0263-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/12582b832bf5/jvirol00221-0264-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/c7c5ade821a3/jvirol00221-0264-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/161219cc969b/jvirol00221-0264-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/dda8c695dffb/jvirol00221-0264-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/3b07285605e5/jvirol00221-0265-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/86cae5594f5e/jvirol00221-0265-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/49881cf995e3/jvirol00221-0265-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/0169282874e7/jvirol00221-0265-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/a06fc3e89199/jvirol00221-0263-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/d9b3ad1dc010/jvirol00221-0263-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/12582b832bf5/jvirol00221-0264-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/c7c5ade821a3/jvirol00221-0264-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/161219cc969b/jvirol00221-0264-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/dda8c695dffb/jvirol00221-0264-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/3b07285605e5/jvirol00221-0265-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/86cae5594f5e/jvirol00221-0265-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/49881cf995e3/jvirol00221-0265-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ac6/515588/0169282874e7/jvirol00221-0265-d.jpg

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引用本文的文献

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本文引用的文献

1
The structure of some Staphylococcus and Pseudomonas phages.一些葡萄球菌和假单胞菌噬菌体的结构。
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Studies on the morphopoiesis of the head of phage T-even. I. Morphological, immunological, and genetic characterization of polyheads.
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Mutations in bacteriophage lambda affecting particle morphogenesis.影响噬菌体λ颗粒形态发生的突变。
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Induced structural defects in T-even bacteriophage.T-偶数噬菌体中的诱导结构缺陷。
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An accurate measurement of the catalase crystal period and its use as an internal marker for electron microscopy.过氧化氢酶晶体周期的精确测量及其作为电子显微镜内部标记物的应用。
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Structure of the tubular variants of the head of bacteriophage T4 (polyheads). II. Structural transition from a hexamer to a 6+1 morphological unit.
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Structure of the tubular variants of the head of bacteriophage T4 (polyheads). I. Arrangement of subunits in some classes of polyheads.噬菌体T4头部管状变体(多面体头部)的结构。I. 某些类别的多面体头部中亚基的排列
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[On the structure of Bacillus subtilis phages and the lysogeny of the host cells].[关于枯草芽孢杆菌噬菌体的结构及宿主细胞的溶源性]
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[Defective morphogenesis of the Bacillus mycoides phage No. 1 head].[蕈状芽孢杆菌噬菌体1号头部的形态发生缺陷]
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