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[对氯苯丙氨酸(PCPA)治疗后类癌综合征患者出现的外源性精神病]

[Exogenous psychosis in a patient with carcinoid syndrome following treatment with p-chlorophenylalanine (PCPA)].

作者信息

Gruner W

出版信息

Psychiatr Clin (Basel). 1975;8(5):266-76.

PMID:131950
Abstract

A case is reported of a patient with carcinoid syndrome who developed a exogenous psychosis while under treatment with the serotonin-inhibitor p-chlorophenylalanine (PCPA). Partial symptoms similar to delirium and schizophrenia were exhibited. The attached literature survey focuses on the psychological side effects of PCPA treatment. A discussion follows concerning noteworthy phenomenological similarities between the case reported and certain forms of amphetamine psychosis. Common biochemical mechanisms are hypothetically stated.

摘要

报告了一例类癌综合征患者,在使用血清素抑制剂对氯苯丙氨酸(PCPA)治疗期间出现了外源性精神病。表现出了类似于谵妄和精神分裂症的部分症状。所附的文献综述聚焦于PCPA治疗的心理副作用。随后讨论了所报告病例与某些形式的苯丙胺精神病之间值得注意的现象学相似性。假设了共同的生化机制。

相似文献

1
[Exogenous psychosis in a patient with carcinoid syndrome following treatment with p-chlorophenylalanine (PCPA)].[对氯苯丙氨酸(PCPA)治疗后类癌综合征患者出现的外源性精神病]
Psychiatr Clin (Basel). 1975;8(5):266-76.
2
[The carcinoid syndrome. A case description with special reference to its therapeutic aspects].[类癌综合征。伴有对其治疗方面特别提及的病例描述]
Med Welt. 1982 Aug 27;33(34):1155-9.
3
[Parachlorophenylalanine and ultrastructure in the carcinoid syndrome].
Rev Clin Esp. 1974 Jan 15;132(1):11-20.
4
Clinical and biochemical effects of parachlorophenylalanine in a patient with the carcinoid syndrome.对氯苯丙氨酸在类癌综合征患者中的临床及生化效应
Postgrad Med J. 1982 Aug;58(682):493-5. doi: 10.1136/pgmj.58.682.493.
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[Enzyme activity (monoamine oxidase, histaminase, kallikreinogen) in carcinoids treated with parachlorophenylalanine].[用对氯苯丙氨酸治疗的类癌中的酶活性(单胺氧化酶、组胺酶、激肽释放酶原)]
Boll Soc Ital Biol Sper. 1975 Sep 15;51(17):1025-30.
6
Octreotide treatment of carcinoid hypertensive crisis.奥曲肽治疗类癌危象性高血压
Mt Sinai J Med. 1994 Sep;61(4):349-55.
7
[Effects of the administration of somatostatin 14 in the carcinoid syndrome. Clinical and biological study of 2 cases].[生长抑素14治疗类癌综合征的效果。2例临床及生物学研究]
Gastroenterol Clin Biol. 1983 Dec;7(12):1016-22.
8
Inhibition of phenylalanine hydroxylation during treatment of carcinoid syndrome with p-chlorophenylalanine.在使用对氯苯丙氨酸治疗类癌综合征期间苯丙氨酸羟化作用的抑制。
Isr J Med Sci. 1970 Jul-Aug;6(4):475-8.
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[Effect of somatostatin and salmon calcitonin on carcinoid syndrome. A clinical case].[生长抑素和鲑鱼降钙素对类癌综合征的影响。1例临床病例]
Minerva Chir. 1989 May 15;44(9):1429-33.
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Octreotide inhibition of flushing and colonic motor dysfunction in carcinoid syndrome.奥曲肽对类癌综合征中潮红和结肠运动功能障碍的抑制作用。
Am J Gastroenterol. 1997 Dec;92(12):2250-6.