在肯尼亚分离出的一种新型蓝舌病毒血清型。

A new bluetongue virus serotype isolated in Kenya.

作者信息

Davies F G, Mungai J N, Pini A

机构信息

Veterinary Research Laboratory, PO Kabete, Kenya.

出版信息

Vet Microbiol. 1992 Apr;31(1):25-32. doi: 10.1016/0378-1135(92)90138-j.

DOI:10.1016/0378-1135(92)90138-j

PMID:1319624

Abstract

An apparently new strain of bluetongue virus was first isolated in Kenya in 1965 and since, has been obtained on 7 further occasions from diseased sheep during clinical outbreaks of disease. It proved to be serologically different from the 16 bluetongue virus strains then held at this laboratory. The virus was modified by passage in embryonated hens eggs to produce a live virus strain suitable for inclusion in a polyvalent vaccine. Recent neutralisation tests, carried out with 24 guinea pig immune sera prepared at Pirbright against the currently known World serotypes, have confirmed the earlier results and show that it is different from any of the existing serotypes.

摘要

1965年，一种明显的新型蓝舌病毒毒株首次在肯尼亚分离出来，此后，在疾病临床暴发期间，又从患病绵羊身上7次分离出该病毒。事实证明，它在血清学上与当时保存在本实验室的16种蓝舌病毒毒株不同。该病毒通过在鸡胚中传代进行改造，以产生一种适合用于多价疫苗的活病毒毒株。最近，用在皮尔布赖特制备的针对当前已知世界血清型的24份豚鼠免疫血清进行的中和试验，证实了早期结果，并表明它与任何现有血清型都不同。