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[脑干梗死的临床特征与发病机制]

[Clinical aspects and pathogenesis of infarction of the brain stem].

作者信息

Lifshits F I, Makarova L D, Solodiankina M E

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1992;92(1):21-4.

PMID:1319640
Abstract

Clinical and hemodynamic studies were carried out in 75 patients with stem brain infarction in the acute period, including repeated infarctions. The total rupture of the autoregulatory mechanisms of the brain blood flow was discovered, leading to the development of different phenomena of "brain steal" determining the clinical course of stem brain infarction. In the given pathology, the acute period is characterized by the development of the vicious circle of hemodynamic disorders, which is coupled with pathological dissociation in coagulation hemostasis. The progression of the hemodynamic changes requires pathogenetic correction of central and cerebral circulation.

摘要

对75例急性期脑干梗死患者(包括反复梗死患者)进行了临床和血液动力学研究。发现脑血流自动调节机制完全破坏,导致不同的“盗血”现象出现,这决定了脑干梗死的临床病程。在这种病理情况下,急性期的特点是血液动力学紊乱的恶性循环的发展,同时伴有凝血止血的病理分离。血液动力学变化的进展需要对中枢和脑循环进行病因学纠正。

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