Thomson N C
Department of Respiratory Medicine, Western Infirmary, Glasgow, UK.
Br Med Bull. 1992 Jan;48(1):205-20. doi: 10.1093/oxfordjournals.bmb.a072535.
It is likely that airway inflammation has an central role in the development and maintenance of the structural and functional abnormalities that characterise asthma. The recognition that asthma is a chronic inflammatory disorder of the airways has resulted in an increased emphasis on the use of anti-inflammatory drugs. The principal anti-inflammatory drugs are corticosteroids and to a lesser extent sodium cromoglycate and nedocromil sodium. Several other drugs and therapies may also have anti-inflammatory effects in asthma. The early use of prophylactic anti-inflammatory agents is advocated in the treatment of chronic asthma. It is hoped that this treatment scheme will result in a reduction in the morbidity and mortality from this common chronic condition.
气道炎症很可能在哮喘所特有的结构和功能异常的发生及维持过程中起核心作用。认识到哮喘是一种气道慢性炎症性疾病，使得人们更加重视使用抗炎药物。主要的抗炎药物是皮质类固醇，其次是色甘酸钠和奈多罗米钠。其他几种药物和疗法在哮喘中也可能具有抗炎作用。在慢性哮喘的治疗中提倡早期使用预防性抗炎药物。希望这种治疗方案能降低这种常见慢性病的发病率和死亡率。
