致癌作用是通过特定蛋白质的不同步降解导致干细胞去分化。 - Suppr

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Carcinogenesis as disdifferentiation of stem cells by desynchronized degradation of selected proteins.

作者信息

Fiala S, Fiala E S

出版信息

Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1976 May 3;86(1):1-12. doi: 10.1007/BF00304929.

DOI:10.1007/BF00304929

PMID:132022

Abstract

摘要

相似文献

Carcinogenesis as disdifferentiation of stem cells by desynchronized degradation of selected proteins.致癌作用是通过特定蛋白质的不同步降解导致干细胞去分化。

Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1976 May 3;86(1):1-12. doi: 10.1007/BF00304929.

[The mitochondrial theory of carcinogenesis].

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Certain effects of p-dimethylaminoazobenzene, deficient diet, and hypotonic media on mitochondrial enzymes in experimental rat-liver carcinogenesis.对二甲氨基偶氮苯、缺乏营养的饮食及低渗介质在实验性大鼠肝癌发生过程中对线粒体酶的某些影响

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Cancer stem cell metabolism.癌症干细胞代谢

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Current and upcoming mitochondrial targets for cancer therapy.当前和即将出现的癌症治疗线粒体靶点。

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Comparative proteomics research on rat MSCs differentiation induced by Shuanglong Formula.双龙方诱导大鼠骨髓间充质干细胞分化的比较蛋白质组学研究。

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ATP-dependent proteolysis of mitochondria of reticulocytes.网织红细胞线粒体的ATP依赖性蛋白水解作用。

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Carcinogenesis is consequence of failure of tissue development.癌变是组织发育失败的结果。

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本文引用的文献

[Experimental carcinogenesis of the parenchymal cell].[实质细胞的实验性致癌作用]

Dtsch Med Wochenschr. 1961 Sep 29;86:1845-50. doi: 10.1055/s-0028-1113014.

[Respiration & glycolysis of rat liver during 4-dimethylaminoazobenzene treatment].[4-二甲基氨基偶氮苯处理期间大鼠肝脏的呼吸与糖酵解]

Z Naturforsch B. 1958 Aug;13B(8):516-25.

Studies on the synthesis and degradation of proteins of the endoplasmic reticulum of rat liver.大鼠肝脏内质网蛋白质合成与降解的研究。

J Biol Chem. 1969 Jun 25;244(12):3303-15.

The cancer cell as a stem cell unable to differentiate. A theory of carcinogenesis.癌细胞作为一种无法分化的干细胞。一种致癌理论。

Neoplasma. 1968;15(6):607-22.

Alterations in turnover of labelled precursors incorporated into rat liver nuclear macromolecules during azo dye feeding.偶氮染料喂养期间掺入大鼠肝细胞核大分子中的标记前体周转变化。

Chem Biol Interact. 1972 Mar;4(4):287-96. doi: 10.1016/0009-2797(72)90023-3.

Demonstration of glucose 6-phosphatase activity in the oval cells of rat liver and the significance of the oval cells in azo dye carcinogenesis.大鼠肝脏卵圆细胞中葡萄糖-6-磷酸酶活性的显示及卵圆细胞在偶氮染料致癌过程中的意义

Cancer Res. 1974 Dec;34(12):3379-86.

Different degradation rates of alkylated RNA protein and lipids in normal and tumor cells.正常细胞和肿瘤细胞中烷基化RNA、蛋白质和脂质的不同降解速率。

Cancer Res. 1974 Jul;34(7):1536-41.

Nonhistone chromosomal proteins and gene regulation.非组蛋白染色体蛋白与基因调控。

Science. 1974 Mar 1;183(4127):817-24. doi: 10.1126/science.183.4127.817.

Accumulation of hepatic mitochondria in 2-methyl-4-dimethyl-aminoazobenzene fed rats as a result of decreased degradation.在喂食2-甲基-4-二甲基氨基偶氮苯的大鼠中，由于降解减少导致肝线粒体积累。

Naturwissenschaften. 1973 Aug;60(8):394-5. doi: 10.1007/BF00602526.

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