乳腺癌行乳房局部切除术后放疗引发的血管肉瘤。
Angiosarcoma after tylectomy and radiation therapy for carcinoma of the breast.
作者信息
Edeiken S, Russo D P, Knecht J, Parry L A, Thompson R M
机构信息
Jersey Shore Medical Center, Neptune, New Jersey.
出版信息
Cancer. 1992 Aug 1;70(3):644-7. doi: 10.1002/1097-0142(19920801)70:3<644::aid-cncr2820700317>3.0.co;2-5.
BACKGROUND
Angiosarcoma (AS) is an uncommon tumor that rarely develops after external beam radiation therapy (EBRT). Thirty-six cases have been reported in the literature.
METHODS
The authors present two additional cases. Each of these patients received breast-conserving treatment for breast carcinoma that consisted of tylectomy and EBRT. In each case, AS developed in the field of prior irradiation.
RESULTS
Currently, seven cases of AS after radiation therapy for breast-conserving treatment of breast carcinoma have been reported. The average time interval between the administration of radiation therapy and the development of AS is 8.6 years.
CONCLUSIONS
This complication is rare and should not influence the decision to offer breast-conserving therapy to patients. However, patients should be informed that AS may develop as a result of radiation therapy.
背景
血管肉瘤（AS）是一种罕见的肿瘤，在外照射放疗（EBRT）后很少发生。文献中已报道36例。
方法
作者介绍另外2例病例。这两名患者均接受了保乳治疗，包括乳房肿瘤切除术和EBRT。在每例病例中，AS均发生在先前放疗区域。
结果
目前，已有7例乳腺癌保乳治疗放疗后发生AS的病例报道。放疗与AS发生之间的平均时间间隔为8.6年。
结论
这种并发症很罕见，不应影响为患者提供保乳治疗的决策。然而，应告知患者放疗可能导致AS发生。
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