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纳米比亚三个主要种族癫痫患者脑电图中光阵发性反应的患病率。

Prevalence of a photoparoxysmal response in the electroencephalograms of epileptics in the three main ethnic groups of Namibia.

作者信息

de Graaf A S

机构信息

Department of Neurology and Clinical Neurophysiology, Tijgerberg Hospital, Republic of South Africa.

出版信息

Clin Neurol Neurosurg. 1992;94 Suppl:S67-9. doi: 10.1016/0303-8467(92)90026-y.

Abstract

This descriptive study consists of 1493 EEGs from patients with epilepsy referred to the State Hospital in Windhoek, over the years 1983-1988. Excluded were patients with febrile convulsions, acute symptomatic epilepsy and a history of alcoholism. A standardized procedure of intermittent photic stimulation (IPS) was performed. The three main population groups blacks, coloureds (people of mixed race) and whites, were adequately represented in the sample. Classical photoparoxysmal responses (PPR) occurred in 0.4, 4.2 and 5.2%, respectively. Climatic factors are not considered relevant in the elicitation of a PPR. It is postulated that different mutations occurred in the genes that were involved in the expression of the PPR in epileptic patients of different ethnic groups.

摘要

这项描述性研究包含了1983年至1988年间转诊到温得和克市立医院的1493例癫痫患者的脑电图。热性惊厥患者、急性症状性癫痫患者和有酗酒史的患者被排除在外。进行了标准化的间歇性光刺激(IPS)程序。样本中充分代表了三个主要人群组:黑人、有色人种(混血人种)和白人。典型光阵发性反应(PPR)的发生率分别为0.4%、4.2%和5.2%。气候因素被认为与PPR的诱发无关。据推测,不同种族癫痫患者中参与PPR表达的基因发生了不同的突变。

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