Ovesen L, Hannibal J, Allingstrup L
Department of Medicine C, Bispebjerg University Hospital, Copenhagen, Denmark.
Eur J Clin Nutr. 1992 Jul;46(7):535-7.
Energy and protein intake in 32 consecutive patients with small cell lung cancer was examined at initiation of cyclical chemotherapy and after 1 and 3 months. With each cycle intakes decreased in the first 2 days following chemotherapy, but were back to pretreatment levels on the third day. Eleven of the patients lost weight in the study period. Their energy and protein intakes were lower following chemotherapy compared to pretreatment intakes and to post-therapy intakes in weight-stable patients. Pretreatment intakes did not decrease over time, either in weight-losing or in weight-stable patients.
对32例连续的小细胞肺癌患者在进行周期性化疗开始时、化疗1个月后和3个月后进行能量和蛋白质摄入量检查。在每个化疗周期中,化疗后的前两天摄入量下降,但在第三天恢复到治疗前水平。在研究期间,11例患者体重减轻。与治疗前摄入量以及体重稳定患者的治疗后摄入量相比,他们化疗后的能量和蛋白质摄入量较低。无论体重减轻患者还是体重稳定患者,治疗前的摄入量均未随时间下降。