Goncharov N, Aso T, Cekan Z, Pachalia N, Diczfalusy E
Acta Endocrinol (Copenh). 1976 Jun;82(2):396-412. doi: 10.1530/acta.0.0820396.
Eleven unconjugated steroids were measured daily during a complete cycle in the peripheral plasma of 6 normally menstruating baboons (Papio hamadryas) by means of a radioimmunoassay procedure and the levels were compared with those found previously in 17 normally menstruating women. The patterns of progesterone and 20alpha-dihydroprogesterone were very similar to those found in women throughout the entire menstrual cycle. However, the ratio of these steroids differed markedly from that found in women. A great similarity of the follicular phase and the peri-ovulatory period profiles was observed in both species for 17-hydroxy-progesterone, pregnenolone, androstenedione, oestradiol and oestrone. The pattern of oestradiol:oestrone ratios was similar in both species. However, an elevation of the above five steroids, typical for the human luteal phase, was not found in baboons. The increase of testosterone values, seen in women at mid-cycle, was not detected in baboons. The plasma concentrations were lower in baboons than in humans for all the above steroids.
通过放射免疫分析法，在6只正常月经周期的狒狒（阿拉伯狒狒）外周血浆中，对11种未结合类固醇进行了一个完整周期的每日测量，并将这些水平与之前在17名正常月经周期女性中测得的水平进行了比较。孕酮和20α-二氢孕酮的模式在整个月经周期中与女性中发现的模式非常相似。然而，这些类固醇的比例与女性中发现的比例明显不同。在两个物种中，17-羟孕酮、孕烯醇酮、雄烯二酮、雌二醇和雌酮在卵泡期和排卵前期的水平轮廓非常相似。雌二醇与雌酮的比例模式在两个物种中相似。然而，狒狒中未发现人类黄体期典型的上述五种类固醇升高的情况。在女性月经周期中期出现的睾酮值升高，在狒狒中未检测到。上述所有类固醇在狒狒中的血浆浓度均低于人类。
