Andersson S A, Hansson G, Holmgren E, Renberg O
Acta Orthop Scand. 1976 Apr;47(2):149-57. doi: 10.3109/17453677608989710.
The pain suppressive effect of low (2/s) and high (50-100/s) frequency electrical stimulation was studied in 12 patients with severe chronic pain in the back and/or the legs. All patients were subjected to a thorough physical examination before and 2-3 weeks after a series of stimulation sessions. The stimulation was applied via surface electrodes to areas both segmentally related and segmentally unrelated to the regions of chronic pain. Low frequency stimulation induced a partial pain relief in only one patient whereas stimulation with high frequency gave a suppression of pain in seven patients. The effect was short-lasting in most cases and the pain started to increase usually within 30 min. It is concluded that the observed pain suppression is not due to psychological factors but to more basic neurophysiological mechanisms. Augmentation of the effect after repeated stimulation sessions was not observed, neither was there any alteration in the neuro-orthopedic status nor any lasting pain relief in any patient.
对12例患有严重慢性背部和/或腿部疼痛的患者，研究了低频率（2次/秒）和高频率（50 - 100次/秒）电刺激的止痛效果。在一系列刺激疗程之前和之后2 - 3周，对所有患者进行了全面的体格检查。通过表面电极将刺激施加于与慢性疼痛区域节段相关和节段不相关的区域。低频刺激仅在1例患者中引起部分疼痛缓解，而高频刺激在7例患者中产生了疼痛抑制。在大多数情况下，这种效果是短暂的，疼痛通常在30分钟内开始加剧。得出的结论是，观察到的疼痛抑制不是由于心理因素，而是由于更基本的神经生理机制。未观察到重复刺激疗程后效果增强，患者的神经骨科状况也未发生任何改变，也没有任何患者获得持久的疼痛缓解。
