Verniers D A, Keus R B, Schouwenburg P F, Bartelink H
Dr. Daniel den Hoed Cancer Centre, Rotterdam, The Netherlands.
Eur J Cancer. 1992;28A(6-7):1028-33. doi: 10.1016/0959-8049(92)90448-b.
Between 1970 and 1990, 22 patients with 44 chemodectomas in the head and neck region were seen at the Netherlands Cancer Institute in Amsterdam. All patients were treated with radiation therapy (17 patients with radiation therapy only and 5 in combination with surgery). One patient was treated two times with an interval of 12 years at each side of the neck. Standard dose was 50 Gy in 25 fractions over 5 weeks. A radiation portal arrangement with oblique fields with paired wedges was used most frequently. The follow-up period ranged from 1 year to 20 years. Two recurrences at 2 and 9 years after treatment were observed. The actuarial local control rate was 88% at 10 years follow-up. Comparison of the results of surgery and radiotherapy demonstrates that radiation therapy is an effective treatment modality without mutilation or severe late morbidity for chemodectomas in the head and neck region.
1970年至1990年间，阿姆斯特丹的荷兰癌症研究所收治了22例头颈部化学感受器瘤患者，共44处病灶。所有患者均接受了放射治疗（17例仅接受放射治疗，5例联合手术治疗）。1例患者颈部两侧各接受了2次放射治疗，间隔时间为12年。标准剂量为50 Gy，分25次，在5周内完成。最常采用的放疗野设置是带有配对楔形板的斜野。随访时间为1年至20年。观察到2例患者在治疗后2年和9年复发。10年随访时的精算局部控制率为88%。手术和放疗结果的比较表明，放射治疗是一种有效的治疗方式，对头颈部化学感受器瘤不会造成毁容或严重的晚期并发症。
