MOORE J G, SINGH B P, HOLZMAN R S
Calif Med. 1954 Nov;81(5):316-20.
Endometrial hyperplasia and irregular shedding of the endometrium comprise the largest group of known causes of functional uterine bleeding.Most patients with functional uterine bleeding have a normal endometrial pattern. In a series of patients with functional uterine bleeding, it was noted that 69.7 per cent of endometrial specimens reported as normal showed evidence of hyalinized tissue which included endometrial glands. Tissue of this type was noted in only 3.5 per cent of curetted specimens from patients without functional uterine bleeding. Diagnostic uterine curettage is the initial step in the management of functional uterine bleeding. Hysterectomy and radiation castration are seldom necessary in the management of functional uterine bleeding and are indicated only under specific circumstances.
子宫内膜增生和子宫内膜不规则脱落是功能性子宫出血已知病因中最主要的类型。大多数功能性子宫出血患者的子宫内膜形态正常。在一组功能性子宫出血患者中，发现报告为正常的子宫内膜标本中有69.7%显示出包括子宫内膜腺体在内的透明化组织迹象。在无功能性子宫出血患者的刮宫标本中，仅3.5%发现了这种类型的组织。诊断性刮宫是功能性子宫出血治疗的第一步。子宫切除术和放射去势在功能性子宫出血的治疗中很少需要，仅在特定情况下适用。
