Moghal N
Department of Histopathology, Dubai Hospital.
J Pak Med Assoc. 1997 Dec;47(12):295-9.
Endometrial curettings from 458 patients presenting with abnormal uterine bleeding were studied. This included 220 (48%) patients with metrorrhagia, 187 (41%) with menorrhagia, 30 (6%) with postmenopausal bleeding, 13 (3%) with intermenstrual bleeding and 8 (1.74%) with polymenorrhagia. The histological findings were correlated with the pattern of abnormal bleeding in five different age groups. In 48.5% of the biopsies, histology assisted in diagnosing the cause of bleeding viz, intrauterine lesion in 25.5% and an ovulatory cycles in 22.9%. The endometrial lesions detected on histopathology included 2 (0.44%) endometrial adenocarcinomas, one (0.21%) carcinosarcoma, one (0.21%) metastatic mucinous adenocarcinoma, 41 (8.95%) benign polyps, 51 (11.1%) endometrial hyperplasia, 15 (3.28%) endometritis and 6 (1.3%) atrophic endometrium. The curettage was found to be of relatively low diagnostic value in menorrhagia and intermenstrual bleeding while its diagnostic yield was high in patients with postmenopausal bleeding and metrorrhagia.
对458例子宫异常出血患者的子宫内膜刮除物进行了研究。其中包括220例（48%）月经过多患者、187例（41%）月经量过多患者、30例（6%）绝经后出血患者、13例（3%）月经间期出血患者和8例（1.74%）月经频发患者。组织学检查结果与五个不同年龄组的异常出血模式相关。在48.5%的活检中，组织学有助于诊断出血原因，即25.5%为宫内病变，22.9%为无排卵周期。组织病理学检测到的子宫内膜病变包括2例（0.44%）子宫内膜腺癌、1例（0.21%）癌肉瘤、1例（0.21%）转移性黏液腺癌、41例（8.95%）良性息肉、51例（11.1%）子宫内膜增生、15例（3.28%）子宫内膜炎和6例（1.3%）萎缩性子宫内膜。发现刮宫术对月经量过多和月经间期出血的诊断价值相对较低，而对绝经后出血和月经过多患者的诊断率较高。
