Bogdanov N N, Voronina T A
Zh Vyssh Nerv Deiat Im I P Pavlova. 1992 May-Jun;42(3):566-72.
The effects of diazepam (5 mg/kg, i.p.) on the EEG power spectra of the sensorimotor cortex and the dorsal hippocampus were studied in albino rats with different types of conflict behaviour. "Active" rats were characterized by domination of the theta-activity in their background cortical EEG-spectra, "passive" ones--by that of the delta-activity. No differences were revealed in the background hippocampal EEG-spectra. Diazepam produced slowing of the theta-activity and increased the beta-activity in a band of 12-32 Hz in "active" rats and that in a band of 12-16 Hz in "passive" ones. The finding is usefull for studying individual animal sensitivity to drugs effects.
研究了地西泮（5毫克/千克，腹腔注射）对具有不同类型冲突行为的白化大鼠感觉运动皮层和背侧海马脑电图功率谱的影响。“活跃”大鼠的特征是其皮层脑电图背景谱中θ活动占主导，“被动”大鼠的特征是δ活动占主导。海马脑电图背景谱未发现差异。地西泮使“活跃”大鼠的θ活动减慢，并增加了12 - 32赫兹频段的β活动，使“被动”大鼠的12 - 16赫兹频段的β活动增加。这一发现有助于研究动物个体对药物作用的敏感性。
