Climent C, Vélez R, Capriles J A
Department of Pathology School of Medicine, Medical Sciences Campus, UPR.
Bol Asoc Med P R. 1992 Jan;84(1):31-3.
Post-transfusion CMV infection most frequently results in asymptomatic seroconversion. Among immunocompetent patients only seronegative pregnant women require such products because of the risk of fetal CMV infection. In selected groups of immunocompromised patients, significant disease can occur. It is desirable to provide blood and blood components with reduced CMV risk to the following patients: seronegative infants weighting less than 1200 g at birth, seronegative bone marrow transplant patients who receive marrow from seronegative donors and seronegative renal transplant patients receiving kidneys from seronegative donors. Heart and liver transplantation seronegative patients may receive seronegative blood if the donor is seronegative. CMV--seronegative HIV infected cases may also be transfused with CMV--seronegative blood.
输血后巨细胞病毒（CMV）感染最常导致无症状血清学转换。在免疫功能正常的患者中，只有血清学阴性的孕妇因有胎儿CMV感染风险而需要此类制品。在特定的免疫功能低下患者群体中，可能会发生严重疾病。对于以下患者，提供CMV风险降低的血液和血液成分是可取的：出生时体重小于1200克的血清学阴性婴儿、接受血清学阴性供体骨髓的血清学阴性骨髓移植患者以及接受血清学阴性供体肾脏的血清学阴性肾移植患者。心脏和肝脏移植血清学阴性患者，如果供体是血清学阴性，则可接受血清学阴性血液。CMV血清学阴性的HIV感染病例也可输注CMV血清学阴性血液。
