ROBERTSON J D
J Biophys Biochem Cytol. 1955 Jul 25;1(4):271-8. doi: 10.1083/jcb.1.4.271.
Adult chameleon myelinated peripheral nerve fibers have been studied with the electron microscope in thin sections. The outer lamella of the myelin sheath has been found to be connected as a double membrane to the surface of the Schwann cell. The inner lamella is connected as a similar double membrane with the double axon-Schwann membrane. The relations of these double connecting membranes suggest that the layered myelin structure is composed of a double membrane which is closely wound about the axon as a helix. These findings support the new theory of myelinogenesis proposed recently by Geren. The possible significance of these results with respect to cell surface membranes and cytoplasmic double membranes is discussed.
用电子显微镜对成年变色龙有髓外周神经纤维进行了薄切片研究。已发现髓鞘的外层片作为双层膜与施万细胞表面相连。内层片作为类似的双层膜与轴突 - 施万细胞双层膜相连。这些双连接膜的关系表明,分层的髓鞘结构由双层膜组成,该双层膜以螺旋形式紧密缠绕在轴突周围。这些发现支持了Geren最近提出的髓鞘形成新理论。讨论了这些结果在细胞表面膜和细胞质双层膜方面可能的意义。