Peltier M K, Filipovich A H, Bechtel M, Dirksen C L, Englund J A
Pharmacy Department, University of Minnesota Hospital and Clinic, Minneapolis 55455.
Semin Hematol. 1992 Jul;29(3 Suppl 2):112-5.
We have used samples from the in vivo situation to compare antibody levels provided by the infusion of different IVIG products, a measure, albeit indirect, of potential therapeutic efficacy. The further correlation of in vivo antibody titers with functional activities of these antibodies (eg, opsonization and viral neutralization) would provide additive valuable information about the usefulness of this therapy.
我们使用了来自体内情况的样本,以比较不同静脉注射免疫球蛋白(IVIG)产品输注所提供的抗体水平,这是一种衡量潜在治疗效果的方法,尽管是间接的。体内抗体滴度与这些抗体的功能活性(如调理作用和病毒中和)的进一步相关性,将为这种治疗方法的有效性提供额外的有价值信息。