Irarrazaval M J, Cosgrove D M, Loop F D, Ennix C L, Groves L K, Taylor P C
J Thorac Cardiovasc Surg. 1977 Feb;73(2):181-8.
Reoperations solely for myocardial revascularization were performed in 219 consecutive patients (1967 to 1975). Indications were (1) graft failure, 46 (21 per cent); (2) progressive atherosclerosis, 42 (19 per cent); (3) incomplete revascularization, 39 (18 per cent); and (4) combinations, 92 (42 per cent). Primary operations included bypass grafts in 100 patients; mammary artery implants, 87; and combinations of direct and indirect procedures, 32. Reoperations performed were single bypass, 141 patients; double, 61; and triple or other coronary artery operations, 17. Eight patients died within 30 days of operation (3.7 per cent). Major postoperative complications included hepatitis, 24 (11 per cent); myocardial infarction, 19 (9 per cent); bleeding, 21 (10 per cent); and respiratory insufficiency, 12 (5 per cent). Follow-up for 202 long-term survivors was complete (mean 29 months). In patients who originally underwent direct revascularization, Class I or II (N.Y.H.A.) was attained in 35 of 43 (81 per cent) of those reoperated upon for primary graft failure, in 14 of 15 (93 per cent) of those with progressive atherosclerosis, and in 27 of 33 (82 per cent) of patients with combined indications. Arteriography was performed after the reoperation in 55 patients (mean interval 17 months), and 65 of 77 (84 per cent) grafts were patent. Nineteen of 22 grafts performed for primary graft failure were patent. We have made the following conclusions: (1) Reoperation for direct myocardial revascularization can be accomplished with low mortality rates although morbidity is high; (2) complete relief of symptoms was achieved in 65 per cent of survivors; (3) results in patients reoperated upon for graft failure alone were similar to results in those operated upon for progressive atherosclerosis or combined indications; and (4) high graft patency was found in secondary grafts constructed to arteries involved with primary graft failure.
1967年至1975年间,对219例连续患者仅进行了心肌血运重建再次手术。手术指征包括:(1)移植血管失败,46例(21%);(2)进行性动脉粥样硬化,42例(19%);(3)血运重建不完全,39例(18%);(4)多种情况组合,92例(42%)。初次手术包括100例行搭桥移植术;87例行乳内动脉植入术;32例行直接和间接手术联合。再次手术中,141例患者行单支搭桥;61例行双支搭桥;17例行三支或其他冠状动脉手术。8例患者在术后30天内死亡(3.7%)。术后主要并发症包括肝炎,24例(11%);心肌梗死,19例(9%);出血,21例(10%);呼吸功能不全,12例(5%)。对202例长期存活者进行了完整随访(平均29个月)。在最初接受直接血运重建的患者中,因原发性移植血管失败而再次手术的43例患者中有35例(81%)达到纽约心脏协会(N.Y.H.A.)Ⅰ级或Ⅱ级;因进行性动脉粥样硬化而再次手术的15例患者中有14例(93%)达到该级别;因多种指征联合而再次手术的33例患者中有27例(82%)达到该级别。55例患者在再次手术后进行了血管造影(平均间隔17个月),77支移植血管中有65支(84%)通畅。因原发性移植血管失败而进行的22支移植血管中有19支通畅。我们得出了以下结论:(1)直接心肌血运重建再次手术虽然发病率高,但死亡率低;(2)65%的存活者症状完全缓解;(3)仅因移植血管失败而再次手术的患者结果与因进行性动脉粥样硬化或多种指征联合而手术的患者结果相似;(4)在与原发性移植血管失败相关的动脉上构建的二次移植血管中发现了较高的移植血管通畅率。