Protas I I, Drakina S A, Nedz'ved' M K, Mil'kamanovich E K
Zh Nevropatol Psikhiatr Im S S Korsakova. 1992;92(2):25-30.
The results of the clinico-morphological studies carried out in 30 patients with the anterior-horn variety of amyotrophic lateral sclerosis (ALS) (CNS morphology was investigated in 6 cases) demonstrate this variety to be characterized by early fading of the tendinous periosteal reflexes, rapid development of amyotrophies, weak intensity of pyramid system lesions. This is supported by morphological studies of the CNS and allows advancing an opinion in favour of the priority of motoneuronal injury.
对30例患有前角型肌萎缩侧索硬化症(ALS)患者进行的临床形态学研究结果(其中6例研究了中枢神经系统形态)表明,该类型的特征为腱膜骨膜反射早期消失、肌萎缩快速发展、锥体系统损伤强度较弱。中枢神经系统的形态学研究支持了这一点,并使人倾向于认为运动神经元损伤更为优先。