[Clinical course of poisoning with volatile substances of "Moment-1" glue].

Clinical and psychopathological methods were employed to examine 30 adolescents aged 13-17 years, who exhibited the liking for inhalation of Moment-1 glue vapours. Adolescents from unhappy and alcoholic families were found to be most prone to the toxicomania type in question. The premorbid condition of the adolescents was characterized by the psychopathological personality traits of the unstable type. The intensity of the psychopathological disorders correlated with the patients' age and residual organic brain injury. Combinations of certain volatile organic solvents contained by Moment-1 glue were found to be highly hallucinogenic and neurotoxic. Neurotoxicity was marked by rapid-growing signs of a decrease of the personality level by the organic type. In some cases, there were acute severe poisonings and lethal outcomes. The adolescents described may be attributed to a group at risk for alcoholism and substance abuse. As a rule, it is necessary to perform multimodality treatment to be given in three stages: detoxication therapy, administration of nootropic agents and correctors of behavior, individual and group psychotherapy.