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[一种不寻常的喉部肿瘤:恶性纤维组织细胞瘤。附病例报告并文献复习]

[An unusual tumor of the larynx: malignant fibrous histiocytoma. Apropos of a case. Review of the literature].

作者信息

Tort C, Tasei-Stefen A M, Darre A, Goubert J L, Raymond-Gelle M C

机构信息

Service d'ORL et de Chirurgie Cervico-faciale, C.H. Henri-Duffaut, Avignon.

出版信息

Ann Otolaryngol Chir Cervicofac. 1992;109(2):100-4.

PMID:1326249
Abstract

On the basis of one case, the authors report about an exceptional tumor of the larynx: malignant fibrous histiocytoma. This tumor, belonging to the soft-tissue sarcomas, usually develops in the limbs. The histological diagnosis is still difficult, in spite of the help provided by immunocytochemistry and fine structural analysis. A histological grading associated to other deciding prognostic factors, such as the size and depth of the tumor and the quality of exeresis, would demonstrate a prognostic correlation. The evolution is characterized by frequent local recurrence and metastases. The treatment is mainly surgical, with as extensive an exeresis as possible at once. Radiation therapy and chemotherapy, though often associated, have not decisively proven their value.

摘要

基于一个病例,作者报告了一种罕见的喉肿瘤:恶性纤维组织细胞瘤。这种肿瘤属于软组织肉瘤,通常发生于四肢。尽管免疫细胞化学和精细结构分析提供了帮助,但组织学诊断仍然困难。与其他决定性预后因素(如肿瘤大小、深度和切除质量)相关的组织学分级将显示出预后相关性。其病程特点是频繁局部复发和转移。治疗主要是手术,尽可能一次性广泛切除。放疗和化疗虽然常联合应用,但尚未明确证明其价值。

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