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The treatment of patients with metastatic melanoma and renal cell cancer using in vitro expanded and genetically-engineered (neomycin phosphotransferase) bulk, CD8(+) and/or CD4(+) tumor infiltrating lymphocytes and bulk, CD8(+) and/or CD4(+) peripheral blood leukocytes in combination with recombinant interleukin-2 alone, or with recombinant interleukin-2 and recombinant alpha interferon.

出版信息

Hum Gene Ther. 1992 Aug;3(4):411-30. doi: 10.1089/hum.1992.3.4-411.

DOI:10.1089/hum.1992.3.4-411
PMID:1326336
Abstract
摘要

相似文献

1
The treatment of patients with metastatic melanoma and renal cell cancer using in vitro expanded and genetically-engineered (neomycin phosphotransferase) bulk, CD8(+) and/or CD4(+) tumor infiltrating lymphocytes and bulk, CD8(+) and/or CD4(+) peripheral blood leukocytes in combination with recombinant interleukin-2 alone, or with recombinant interleukin-2 and recombinant alpha interferon.使用体外扩增并经基因工程改造(新霉素磷酸转移酶)的大量CD8(+)和/或CD4(+)肿瘤浸润淋巴细胞以及大量CD8(+)和/或CD4(+)外周血白细胞,联合单独使用重组白细胞介素-2,或联合重组白细胞介素-2和重组α干扰素,治疗转移性黑色素瘤和肾细胞癌患者。
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2
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