Frank Y, Vishnubhakat S M, Pahwa S
Department of Neurology, North Shore University Hospital, Manhasset, New York 11030.
Pediatr Neurol. 1992 Jul-Aug;8(4):262-6. doi: 10.1016/0887-8994(92)90362-3.
Brainstem auditory evoked responses were measured in 16 infants and children with acquired immunodeficiency syndrome (AIDS) and in 9 normal infants and children. Two stimulation rates were used: a conventional rate of 10 Hz and a high rate of 50 Hz. Latencies of waves III, IV, and V on the left were significantly longer in the AIDS group when a stimulation rate of 10 Hz was used. With a higher stimulation rate of 50 Hz, significant differences between the two groups occurred in the latencies of waves I, III, and V bilaterally, but there were no significant differences in the interpeak latencies. A measure of the differential effect of the increasing stimulus rate on the two groups was significant for wave I latency and for I-III and I-V interpeak latencies on the left, revealing that increasing stimulation rate prolongs these measures more in the AIDS group. Increased brainstem auditory evoked response stimulation rate may unmask abnormalities in infants and children with AIDS that are not observed when the lower stimulation rate is used.
对16名患有获得性免疫缺陷综合征（艾滋病）的婴幼儿及儿童以及9名正常婴幼儿及儿童进行了脑干听觉诱发电位测量。使用了两种刺激速率：传统的10Hz速率和较高的50Hz速率。当使用10Hz刺激速率时，艾滋病组左侧波III、IV和V的潜伏期显著更长。在50Hz的较高刺激速率下，两组在双侧波I、III和V的潜伏期存在显著差异，但峰间期潜伏期无显著差异。对两组刺激速率增加的差异效应进行测量发现，左侧波I潜伏期以及I-III和I-V峰间期潜伏期存在显著差异，这表明增加刺激速率在艾滋病组中使这些测量值延长得更多。增加脑干听觉诱发电位刺激速率可能会揭示出在使用较低刺激速率时未观察到的艾滋病婴幼儿及儿童的异常情况。
