Popescu V, Antrasian A
Clinica de Pediatrie, Spitalul Clinic Sf. Pantelimon, Bucureşti.
Pediatrie (Bucur). 1992 Jul-Sep;41(3):3-14.
The paper reports, starting from recent data in the literature, an important aspect in a pediatric practice, referring to the congenital qualitative platelet disorders. The authors present a modern classification of platelet disorders, based on functional and biochemical defects: defects of adhesion, of primary aggregation, abnormalities of secretion and procoagulant activity. It is discussed the pathogeny, clinical aspects and laboratory tests of each disease. The authors also present some entities recently individualised an the basis of the most topical literature data and the treatment means used, the evolution and prognosis.
本文从文献中的最新数据出发，报道了儿科实践中的一个重要方面，即先天性血小板质量异常疾病。作者基于功能和生化缺陷，提出了血小板疾病的现代分类：黏附缺陷、初级聚集缺陷、分泌异常和促凝血活性异常。文中讨论了每种疾病的发病机制、临床方面和实验室检查。作者还根据最新的文献数据介绍了一些最近确定的疾病实体、所采用的治疗方法、病情演变和预后。
