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Comparative studies of neoplastic response to a single dose of nitroso compounds. 5. The effect of dimethylnitrosamine in Swiss, ASW/SN and A-strain mice.

作者信息

Cardesa Y I, Patil K, Althoff J, Pour P

出版信息

Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1976 Jun 15;86(2):165-70. doi: 10.1007/BF00284004.

DOI:10.1007/BF00284004
PMID:132789
Abstract

The tumorigenic effect of dimethylnitrosamine given once at 5 different dose levels was compared in adult Swiss, ASW/SN and A-strain mice. Considering the overall tumour incidence, at the highest dose level an increase was found in Swiss and ASW/SN mice, but not in A-strain animals. However, the effect of treatment was unequivocal for lung neoplasms. The rate of carcinomas rose significantly in all 3 strains, although a clear dose response-relationship could be established only in Swiss and ASW/SN mice. A dose-dependent effect for adenomas was found solely in Swiss mice.

摘要

相似文献

1
Comparative studies of neoplastic response to a single dose of nitroso compounds. 5. The effect of dimethylnitrosamine in Swiss, ASW/SN and A-strain mice.
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1976 Jun 15;86(2):165-70. doi: 10.1007/BF00284004.
2
The syncarcinogenic effect of methylcholanthrene and dimethylnitrosamine in Swiss mice.甲基胆蒽与二甲基亚硝胺对瑞士小鼠的同步致癌作用。
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3
The inhibition of dimethylnitrosamine-induced renal tumorigenesis in NZO/Bl mice by orchiectomy.睾丸切除术对NZO/Bl小鼠二甲基亚硝胺诱导的肾肿瘤发生的抑制作用。
Invest Urol. 1975 Sep;13(2):136-41.
4
Comparative studies of neoplastic response to a single dose of nitroso compounds. 4. The effect of dimethyl- and diethyl-nitrosamine in Swiss mice.单剂量亚硝基化合物致癌反应的比较研究。4. 二甲基和二乙基亚硝胺对瑞士小鼠的影响。
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1974;81(3-4):229-33. doi: 10.1007/BF00305023.
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Lung tumorigenesis in mice after chronic exposure in early life to a low dose of dimethylnitrosamine.
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6
Toxicity, tissue changes, and tumor induction in inbred Swiss mice by methylnitrosamine and -amide compounds.
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Carcinogenicity of dimethylnitrosamine in Swiss mice.二甲基亚硝胺对瑞士小鼠的致癌性。
Br J Cancer. 1966 Dec;20(4):871-6. doi: 10.1038/bjc.1966.100.
8
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Effect of cumulative dose and dose rate on dimethylnitrosamine oncogenesis in RF mice.累积剂量和剂量率对RF小鼠二甲基亚硝胺致癌作用的影响。
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本文引用的文献

1
INDUCTION OF MALIGNANT TUMORS IN VARIOUS STRAINS OF MICE BY ORAL ADMINISTRATION OF N-NITROSODIMETHYLAMINE AND N-NITROSODIETHYLAMINE.
Gan. 1965 Apr;56:189-99.
2
CARCINOGENESIS STUDY WITH DIMETHYLNITROSAMINE ADMINISTERED ORALLY TO ADULT AND SUBCUTANEOUSLY TO NEWBORN BALB-C MICE.对成年BALB - C小鼠经口给予二甲基亚硝胺、对新生BALB - C小鼠皮下给予二甲基亚硝胺的致癌性研究。
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3
MALIGNANT TUMORS INDUCED IN MICE FED WITH N-NITROSODIMETHYLAMINE.用N-亚硝基二甲胺喂养的小鼠诱发的恶性肿瘤
Gan. 1963 Dec;54:465-72.
4
[Urethan carcinogenesis in newborn, suckling, and adult mice of C57BL, C3H, BC3F1, C3Hf, and SWR strains].[C57BL、C3H、BC3F1、C3Hf和SWR品系新生、哺乳及成年小鼠的氨基甲酸乙酯致癌作用]
Tumori. 1967 Mar-Apr;53(2):81-102. doi: 10.1177/030089166705300201.
5
Pulmonary and hepatic oncogenesis during treatment of male RF mice with dimethyl-nitrosamine.用二甲基亚硝胺治疗雄性RF小鼠期间的肺和肝肿瘤发生
J Natl Cancer Inst. 1968 Nov;41(5):1213-27.
6
Effect of cumulative dose and dose rate on dimethylnitrosamine oncogenesis in RF mice.累积剂量和剂量率对RF小鼠二甲基亚硝胺致癌作用的影响。
J Natl Cancer Inst. 1970 Sep;45(3):495-8.
7
A study of nitrosamines and S-carboxyl derivatives of cysteine as lung carcinogens in adult SWR mice.成年SWR小鼠中作为肺癌致癌物的亚硝胺和半胱氨酸S-羧基衍生物的研究。
Int J Cancer. 1970 Jul 15;6(1):69-73. doi: 10.1002/ijc.2910060111.
8
A critical review of experiments in chemical carcinogensis using newborn animals.对使用新生动物进行化学致癌实验的批判性综述。
Cancer Res. 1968 Apr;28(4):727-38.
9
Vascular tumors in female mice after intraperitoneal injection of dimethylnitrosamine.
J Natl Cancer Inst. 1973 Jul;51(1):201-8. doi: 10.1093/jnci/51.1.201.
10
Differences in tumor types and organ susceptibility in BALB-c and RF mice following dimethylnitrosamine and diethylnitrosamine.二甲基亚硝胺和二乙基亚硝胺作用后BALB-c小鼠和RF小鼠在肿瘤类型及器官易感性方面的差异
Cancer Res. 1971 Feb;31(2):196-8.