Cramer M J, Slee P H, Schramel F M, Vanderschueren R G, Wagenaar S
Afd. Inwendige Geneeskunde, St. Antonius Ziekenhuis, Nieuwegein.
Ned Tijdschr Geneeskd. 1992 Oct 17;136(42):2082-4.
Small-cell lung cancer may be accompanied by hypercortisolism due to secretion of adrenal stimulating peptides. This occurs almost exclusively in case of extensive disease. The neuroendocrine cell, from which these tumours may originate, plays an important part in the production of these peptides. Four patients are described with small-cell lung cancer and clinical presentation of hypercortisolism, particularly manifesting itself with hypokalaemia.
小细胞肺癌可能因肾上腺刺激肽的分泌而伴有皮质醇增多症。这种情况几乎仅发生在广泛期疾病中。这些肿瘤可能起源的神经内分泌细胞在这些肽的产生中起重要作用。本文描述了4例患有小细胞肺癌且有皮质醇增多症临床表现的患者,尤其表现为低钾血症。