Gomazkov O A, Komissarova N V
Biull Eksp Biol Med. 1976 May;81(5):632-4.
Prekallikrein, plasminogen and prothrombin of human blood plasma have been separately activated by caolin streptokinase and thromboplastin. By measuring the TAME-esterase (N-d Tozy-L-arginine methyl ester) activity of each enzyme and its changes in the course of plasma incubation with the activator, it was possible to estimate the values of precursors of kallikrein, plasmin, thrombin and their inhibitors. Evidence is given that under conditions described the activation is specific of each enzyme and does not affect the level of the two other percursors. The method has been developed in two modifications, permitting to obtain the value of seven parameters in 0.4--0.7 ml of blood plasma.
人血浆中的前激肽释放酶、纤溶酶原和凝血酶原已分别被高岭土链激酶和凝血活酶激活。通过测量每种酶的TAME酯酶（N-d-对甲苯磺酰-L-精氨酸甲酯）活性及其在血浆与激活剂孵育过程中的变化，可以估算激肽释放酶、纤溶酶、凝血酶及其抑制剂前体的值。有证据表明，在所述条件下，激活对每种酶具有特异性，并且不影响其他两种前体的水平。该方法已开发出两种改进形式，能够在0.4 - 0.7毫升血浆中获得七个参数的值。
