Pierre-Kahn A, Cinalli G, Lellouch-Tubiana A, Villarejo F J, Sainte-Rose C, Pfister A, Couly G
Hôpital des Enfants Malades, Paris, France.
Pediatr Neurosurg. 1992;18(1):6-15. doi: 10.1159/000120636.
Three cases of melanotic neuroectodermal tumors of infancy are presented. Two were localized on the midline, involving the skull and extending subdurally. One was located on the inner aspect of the dura and developed intracranially. Two had a benign course following gross total removal. One had a malignant course, recurring locally and spreading within the brain. The difficulties of removing these tumors when they are implanted on the midline are stressed. Histological features of prognostic value are pointed out. Further support for neural crest origin of these tumors is given.
本文报告了3例婴儿黑色素性神经外胚层肿瘤。2例位于中线，累及颅骨并硬膜下扩展。1例位于硬脑膜内侧面，发生于颅内。2例在肿瘤全切后病程呈良性。1例病程呈恶性，局部复发并在脑内播散。强调了这些肿瘤位于中线时切除的困难。指出了具有预后价值的组织学特征。进一步支持了这些肿瘤起源于神经嵴的观点。
