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中国8省儿童出生缺陷流行病学研究

[Epidemiology of birth defects among children in 8 provinces in China].

作者信息

Lei Z

机构信息

Sichuan Family Planning Research Institute, Chengdu.

出版信息

Zhonghua Yi Xue Za Zhi. 1992 Jul;72(7):412-5, 446-7.

PMID:1330231
Abstract

In 1988, birth defects (BD) among 85,170 children aged 0-14 were investigated in eight provinces and cities of China. The overall prevalence rate was 15.13% in urban, 15.40% in rural areas. The prevalence rate of BD was significantly higher in males than in females (16.66% vs 13.70%). The prevalence rate of BD was significantly higher in mothers aged > or = 35 years than in mothers aged < 35. 20 of 82 categories of BD accounted for > or = 1% of all BD. The 3 leading BD were: cutis angioma, congenital heart disease and indirect hernia. The incidence of mental retardation was significantly higher in children with BD than in children without BD.

摘要

1988年,在中国八个省市对85170名0至14岁儿童的出生缺陷(BD)情况进行了调查。城市地区总体患病率为15.13%,农村地区为15.40%。BD的患病率男性显著高于女性(16.66%对13.70%)。母亲年龄≥35岁的BD患病率显著高于年龄<35岁的母亲。82种BD类别中有20种占所有BD的≥1%。排在前三位的BD是:皮肤血管瘤、先天性心脏病和腹股沟斜疝。有BD的儿童智力发育迟缓的发生率显著高于无BD的儿童。

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