• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

[不同乙醇戒断时间的慢性酒精中毒大鼠脑多巴胺和γ-氨基丁酸受体的特性]

[The properties of the brain dopamine and GABA receptors in rats with chronic alcoholic intoxication with different ethanol withdrawal times].

作者信息

Vekshina N L

出版信息

Eksp Klin Farmakol. 1992 May-Jun;55(3):65-7.

PMID:1333864
Abstract

Marked changes in dopamine and GABA receptors in the brain of rats with chronic alcohol intoxication were registered 48 h and 3 months after ethanol withdrawal. The changes in dopamine receptors characterized by the increased number of the sites of binding with ligand (Bmax) were most pronounced 48 h after ethanol withdrawal. In 3 months the properties of these receptors tended toward recovery. The changes in GABA receptors also manifested by the increase in Bmax become further pronounced 3 months after ethanol withdrawal.

摘要

在慢性酒精中毒大鼠戒酒后48小时和3个月时，其大脑中的多巴胺和GABA受体出现了显著变化。多巴胺受体的变化表现为与配体结合位点数量（Bmax）增加，在戒酒后48小时最为明显。3个月时，这些受体的特性趋于恢复。GABA受体的变化同样表现为Bmax增加，在戒酒后3个月变得更加明显。

相似文献

1
[The properties of the brain dopamine and GABA receptors in rats with chronic alcoholic intoxication with different ethanol withdrawal times].[不同乙醇戒断时间的慢性酒精中毒大鼠脑多巴胺和γ-氨基丁酸受体的特性]
Eksp Klin Farmakol. 1992 May-Jun;55(3):65-7.
2
[The neurochemical mechanisms underlying possible recurrences of alcoholism].
Eksp Klin Farmakol. 1992 May-Jun;55(3):67-70.
3
[Neuromediator systems in the mechanisms of remission and recurrence in alcoholism].[酒精中毒缓解与复发机制中的神经介质系统]
Eksp Klin Farmakol. 1995 Sep-Oct;58(5):62-4.
4
[The action of low doses of bromocryptin in experimental morphine abstinence in rats].[低剂量溴隐亭对大鼠实验性吗啡戒断的作用]
Farmakol Toksikol. 1991 May-Jun;54(3):15-7.
5
The lack of CB1 receptors prevents neuroadapatations of both NMDA and GABA(A) receptors after chronic ethanol exposure.CB1受体的缺失可防止慢性乙醇暴露后NMDA和GABA(A)受体的神经适应性变化。
J Neurochem. 2007 Aug;102(3):741-52. doi: 10.1111/j.1471-4159.2007.04577.x. Epub 2007 Apr 17.
6
[The effect of saltwort, Salsola collina, on the phospholipid composition of different sections of the rat brain after ethanol administration and its withdrawal].[盐地碱蓬对乙醇给药及戒断后大鼠脑不同部位磷脂组成的影响]
Eksp Klin Farmakol. 1999 Sep-Oct;62(5):52-3.
7
[Glucose consumption by the rat brain in ethanol intoxication and the abstinence syndrome].[乙醇中毒及戒断综合征时大鼠脑的葡萄糖消耗]
Patol Fiziol Eksp Ter. 1992 Jan-Feb(1):9-12.
8
Neuropeptide S receptor gene expression in alcohol withdrawal and protracted abstinence in postdependent rats.依赖后大鼠酒精戒断和长期戒断时神经肽 S 受体基因的表达。
Alcohol Clin Exp Res. 2010 Jan;34(1):90-7. doi: 10.1111/j.1530-0277.2009.01070.x. Epub 2009 Oct 23.
9
[Changes in the number of benzodiazepine receptors in different parts of the brain of rats after neuroleptic withdrawal].[抗精神病药物撤药后大鼠大脑不同部位苯二氮䓬受体数量的变化]
Biull Eksp Biol Med. 1984 Oct;98(10):457-9.
10
[The brain dopamine receptors in chronically alcoholized animals with different relationships to alcohol].[长期饮酒的动物中与酒精有不同关系的脑多巴胺受体]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1992 Jan-Feb;42(1):168-71.