Araujo G W, Silva A M, Pesquero J B, Lindsey C J, Beraldo W T, Pesquero J L
Department of Physiology and Biophysics, Universidade Federal de Minas Gerais, Belo Horizonte; São Paulo, Brazil.
Agents Actions Suppl. 1992;38 ( Pt 3):23-30.
rSMT3, a tonin like angiotensin II generating enzyme present in rSMG presents a potent oxytocic effect on the isolated rat uterus, which was blocked by a B2 bradykinin receptor antagonist. Under optimal conditions of pH, rSMT3 liberates kinin at rate 19-fold greater than angiotensin II.
rSMT3是一种存在于大鼠颌下腺中的类肾素血管紧张素II生成酶，对离体大鼠子宫呈现出强效催产素样作用，该作用可被B2缓激肽受体拮抗剂阻断。在最佳pH条件下，rSMT3释放激肽的速率比血管紧张素II高19倍。
