Carmignani M, Preziosi P, Del Carmine R, Porcelli G, Volpe A R
Dept. of Cell Biology and Physiology, University of L'Aquila, Italy.
Agents Actions Suppl. 1992;38 ( Pt 3):243-7.
Exposure to vanadate was found to induce arterial hypertension through effects on renin-angiotensin-aldosterone, renal peptidergic, and central and peripheral catecholaminergic systems. Vanadate increased, mainly in vascular myocells, both receptor-operated Ca2+ channel- and cyclic-AMP-dependent availability of Ca2+ for contractile processes. Vanadate was selectively accumulated by tissues in the +4 oxidation state (vanadyl).
