Fronistas O, Stavraka-Kakavaki A, Giougi A, Papatheophanis J
Department of Nuclear Medicine, Athens University, Areteion Hospital, Athens, Greece.
Clin Nucl Med. 1992 Dec;17(12):954-7. doi: 10.1097/00003072-199212000-00010.
Hyperplasia of the parathyroid glands usually is treated surgically by total parathyroidectomy, which would deprive the patient of the parathormone essential for calcium metabolism. The postoperative management of patients submitted to total parathyroidectomy consists either in oral administration of vitamin D and calcium, or in the transplantation of parathyroid tissue, which would produce the required parathormone. The purpose of this study is the scintigraphic assessment of parathyroid tissue transplantation patients. Eighteen patients were examined in the immediate and during a later postoperative period. The examination had three parts. The first one consisted of the assessment of the viability and function of the transplant by dynamic study, using TI-201. The second part consisted of the acquisition of static images of the transplant, and the third part was investigation for possible remnants of pathologic parathyroid tissue in the neck by dual tracer (TI-201/Tc-99m) subtraction imaging.
甲状旁腺增生通常通过甲状旁腺全切除术进行手术治疗,这会使患者失去对钙代谢至关重要的甲状旁腺激素。接受甲状旁腺全切除术的患者术后管理包括口服维生素D和钙,或移植甲状旁腺组织,后者会产生所需的甲状旁腺激素。本研究的目的是对甲状旁腺组织移植患者进行闪烁显像评估。对18例患者在术后即刻及稍后阶段进行了检查。该检查分为三个部分。第一部分包括通过使用铊-201的动态研究评估移植物的活力和功能。第二部分包括获取移植物的静态图像,第三部分是通过双示踪剂(铊-201/锝-99m)减影成像检查颈部是否存在病理性甲状旁腺组织残留。