Chao W C, Wang P C, Wen M, Chang K C, Wang H L
Plastic and Reconstractive Surgery, VGH-Taichung.
Zhonghua Yi Xue Za Zhi (Taipei). 1992 Oct;50(4):347-52.
Leiomyosarcoma is an uncommon tumor that rarely occurred in extremity. Multiple leiomyosarcomas in different extremities is even rarer. We report a 90 year-old male veteran who was found to have four leiomyosarcomas, one in right arm and the other three in right thigh. The patient sustained gunshot injuries over right thigh and right arm about 60 years ago in a war with severe wound sepsis due to open communited fracture of the femur. These tumors happened to distribute in the vicinity of the old scars. It was speculated that these multicentric tumors were due to decreased immune surveillance caused by aging and induced by the previous trauma. The literatures were reviewed and the diagnostic methods, surgical treatment and the adjuvant therapy were discussed.
平滑肌肉瘤是一种罕见的肿瘤，很少发生于四肢。不同肢体出现多发平滑肌肉瘤的情况更为罕见。我们报告一例90岁男性退伍军人，其被发现患有4个平滑肌肉瘤，1个在右臂，另外3个在右大腿。该患者约60年前在一场战争中右大腿和右臂遭受枪伤，因股骨开放性粉碎性骨折导致严重伤口脓毒症。这些肿瘤恰好分布在旧瘢痕附近。据推测，这些多中心肿瘤是由于衰老导致免疫监视功能下降，并由先前的创伤诱发。我们回顾了相关文献并讨论了诊断方法、手术治疗及辅助治疗。
