Mel'kumiants A M, Balashov S A, Klimachev A N, Kartamyshev S P, Khaiutin V M
Fiziol Zh SSSR Im I M Sechenova. 1992 Apr;78(4):61-7.
I. v. administration of inhibitors of endothelium-mediated synthesis of the oxide of nitrogen raised the arterial blood pressure, constricted the femoral artery and decreased the acetylcholine- and ATP-induced vaso-dilatation in anesthetized cats. However, the dilatation induced by an increased blood flow velocity, was not affected. The data obtained suggest that the endothelium-dependent arterial dilatation is not mediated by oxide of nitrogen formed from L-arginine.
静脉注射内皮介导的一氧化氮合成抑制剂可使麻醉猫的动脉血压升高、股动脉收缩，并降低乙酰胆碱和ATP诱导的血管舒张。然而，由血流速度增加引起的血管舒张不受影响。所获得的数据表明，内皮依赖性动脉舒张不是由L-精氨酸生成的一氧化氮介导的。
